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Communication | Special issue | Vol 5, No. 1, 1976, pp.127-134
Published online, 1st January, 1970
DOI: 10.3987/S-1976-01-0127
The Condensation of Histamine with Carbonyl Compounds

Gerhard G. Hebermehl* and Wolfgang Ecsy

*Institut für Organische Chemie, Technische Hochschule Darmstadt, Petersenstrasse. 22 64287 Darmstadt, Germany


Substances of the spinaceamine type, 4,5,6,7-tetrahydroimidazo[5,6-c]pyridines can be obtained, by a biogenetic type synthesis, from histamine and carbonyl compounds in a buffer solution at pH 7.2 with an optimum yield.