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Communication | Special issue | Vol 77, No. 1, 2009, pp.233-239
Published online, 28th August, 2008
DOI: 10.3987/COM-08-S(F)49
Palladium-catalyzed Coupling of N-Heteroaryl Sulfides with Organozinc Reagents

Takahiro Koshiba, Tohru Miyazaki, Hidetoshi Tokuyama, and Tohru Fukuyama*

*Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Aramaki, Aoba-ku, Sendai 980-8578, Japan

Abstract

The palladium-catalyzed cross-coupling of N-heteroaryl sulfides with organozinc reagents was developed. Scope and limitation of the reaction regarding generality of zinc reagents and substrate were also investigated.