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Communication | Special issue | Vol 77, No. 2, 2009, pp.793-800
Published online, 11th September, 2008
DOI: 10.3987/COM-08-S(F)73
Uncariagambiriine and Gambircatechol: Novel Constituents of Uncaria gambir Leaves

Naomi Yoshikado, Shoko Taniguchi, Naoki Kasajima, Fumiaki Ohashi, Kou-Ichi Doi, Takashi Shibata, Takashi Yoshida, and Tsutomu Hatano*

*Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 1-1-1 Tsushima-naka, Okayama 700-8530, Japan

Abstract

Two new polyphenolic compounds, uncariagambiriine (1) and gambircatechol (2), were isolated from Uncaria gambir leaves, along with dehydrodicatechin A (3), catechin-(8→6’)-catechin (4), catechin-(6→6’)-catechin (5), and (+)-catechin (6). The structures of the new compounds, one of which is composed of an indole alkaloid and (+)-catechin, were established based on spectroscopic data.