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Paper | Special issue | Vol 79, No. 1, 2009, pp.635-645
Published online, 10th November, 2008
DOI: 10.3987/COM-08-S(D)29
Synthesis of Nb-Acyltryptamines and Their 1-Hydroxy-tryptamine Derivatives as New α2-Blockers

Koji Yamada, Yoshio Tanaka, and Masanori Somei*

*Faculty of Pharmaceutical Sciences, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma, Kanazawa, Ishikawa 920-1192, Japan


Nb-Acyl- and Nb-acyl-1-hydroxytryptamines are found to be novel and structurally simple α2-blocker for the treatment of erectile dysfunction.