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Note | Regular issue | Vol 78, No. 6, 2009, pp.1563-1567
Published online, 2nd February, 2009
DOI: 10.3987/COM-08-11636
Rumphellolide H, a New Natural Caryophyllane from the Gorgonian Rumphella antipathies

Tsong-Long Hwang, Yin-Di Su, Wan-Ping Hu, Li-Fan Chuang, and Ping-Jyun Sung*

* , National Museum of Marine Biology and Aquarium, 2 Houwan Road, Checheng, Pingtung, Taiwan 944, Taiwan, R.O.C.

Abstract

A new natural caryophyllane-type sesquiterpenoid, rumphellolide H (1), which possesses a tetrahydropyran moiety in structure, was isolated from the gorgonian coral Rumphella antipathies. The structure of 1 was established by spectral data analysis and this metabolite showed moderate inhibitory effects on elastase release by human neutrophils.