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Note | Regular issue | Vol 78, No. 11, 2009, pp.2827-2835
Published online, 31st July, 2009
DOI: 10.3987/COM-09-11773
Two New Sesquiterpene Glucosides from Gymnaster koraiensis

Il Kyun Lee, Ki Hyun Kim, Shi Yong Ryu, and Kang Ro Lee*

*Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University, 300 Chunchun-dong, Jangan-ku, Wuwon 440-746, Korea

Abstract

Two new sesquiterpene glucosides, 1(R),4β-dihydroxy-trans-eudesm-6-ene-1-O-β-D-glucopyranoside (1) and 1(R),4β-dihydroxy-trans-eudesm-7-ene-1-O-β-D-glucopyranoside (2), together with six other known compounds, were isolated from the flowers of Gymnaster koraiensis (Nakai) Kitamura (Compositae). The identification and structural elucidation of these compounds were based on 1D- and 2D-NMR spectral data analysis. The absolute configurations of 1 and 2 were determined by a convenient Mosher ester procedure carried out in NMR tube.