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Obituary
Yoshito Kishi (1937-2023)
Yoshito Kishi (1937-2023)
Professor. Yoshito Kishi,
a member of the Honorary Editorial Associates of HETEROCYCLES,
has passed away on January 9, 2023 at the age of 85.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
January 13, 2023
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Note | Regular issue | Vol 81, No. 4, 2010, pp.985-990
Published online, 9th February, 2010
Published online, 9th February, 2010
DOI: 10.3987/COM-09-11895
■ Peptide Mass Spectrometry by Ionic Probe Attachment Ionization Using NHS-TMpybox and Mal-TMpybox
Fumihiro Ito and Kentaro Yamaguchi*
*Faculty of Pharmaceutical Sciences at Kagawa Campus, Tokushima Bunri University, 1314-1 Shido, Sanuki City, Kagawa 769-2193, Japan
Abstract
The application of a new ionization method that uses metal-complex-based ionization probes containing the 2,6-bis(oxazolinyl)pyridine (pybox) ligand for bioactive peptides is presented. Bradykinin, angiotensin-I, angiotensin-II, and nociceptine as well as a couple of pentapeptides were analyzed. This method was proven to effectively ionize large complex molecules, including biomolecules.
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