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Note | Regular issue | Vol 81, No. 8, 2010, pp.1931-1935
Published online, 24th June, 2010
DOI: 10.3987/COM-10-11989
Naphthopyrones from Cultured Lichen Mycobionts of Pyrenula sp.

Yukiko Takenaka, Naotaka Nagakura, Nobuo Hamada, and Takao Tanahashi*

*Kobe Pharmaceutical University, 4-19-1 Motoyamakita-machi, Higashinada-ku, Kobe 658-8558, Japan


Spore-derived mycobionts of the lichen Pyrenula sp. were cultivated on a malt-yeast extract medium supplemented with 10% sucrose and their metabolites were investigated. A new naphthopyrone derivative, pyrenulin, as well as toralactone were isolated. Their structures were determined by spectroscopic methods. This is the first instance of the isolation of naphthalene derivatives from lichen mycobionts.