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Short Paper | Special issue | Vol 84, No. 2, 2012, pp.1217-1226
Published online, 26th May, 2011
DOI: 10.3987/COM-11-S(P)11
Access to Some UV Chromophore-Containing Antimalarial Trioxanes Using Hydrogen Peroxide as Source of the Peroxy Bonds

Yun Li, Sergio Wittlin, and Yikang Wu*

*State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, 345 Lingling Road, Shanghai 200032, China


Several trioxanes were synthesized through perhydrolysis of an allylic epoxide followed by ketal exchange with a proper dimethyl ketal.