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Short Paper | Regular issue | Vol 83, No. 7, 2011, pp.1649-1658
Published online, 26th April, 2011
DOI: 10.3987/COM-11-12232
Synthesis of Fluorescence Pyriproxyfen Analogues as Juvenile Hormone Agonists

Hideki Abe, Akimi Sato, Shin-ichi Tokishita, Toshihiro Ohta, and Hisanaka Ito*

*Laboratory of Bioorganic Chemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan

Abstract

Four fluorescence analogues of juvenile hormone agonist pyriproxyfen were designed and synthesized. The synthetic analogue having a dimethylamino group exhibited fluorescence, and therefore can be used for investigation of the mode of action of pyriproxyfen as a juvenile hormone analogue.