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Short Paper | Regular issue | Vol 85, No. 2, 2012, pp.413-419
Published online, 8th December, 2011
DOI: 10.3987/COM-11-12380
Tumonoic Acids K and L, Novel Metabolites from the Marine-Derived Fungus Penicillium citrinum

Li Chen,* Kai Huang, Ping Zhong, Xiao Hu, Zhe-Xiang Fang, Jiu-lin Wu, and Qi-Qing Zhang*

*Institute of Biomedical and Pharmaceutical Technology & College of Chemistry and Chemical Engineering, Fuzhou University, No. 523, Gongye Road, Fuzhou City, 350002, China

Abstract

Three new compounds, namely tumonoic acids K (1), L (2), and methyl 2-(2-acetyl-3,5-dihydroxy-4,6-dimethylphenyl)acetate (3), together with nine known compounds, were isolated from the marine-derived fungus Penicillium citrinum. The structures of these compounds were elucidated by spectroscopic methods and chemical derivatization. This study is the first to report on tumonoic acid analogues derived from a fungus.