Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,320 (Yen only)
Period: This Article can be accessed for 7 days.

Short Paper | Regular issue | Vol 85, No. 4, 2012, pp.911-917
Published online, 28th February, 2012
DOI: 10.3987/COM-12-12431
Novel Synthesis of 1,4-Phenylene Bridged Bis-Heterocyclic Tropone Compounds

Yang Li, Feng Li, and Wentao Gao*

*Institute of Superfine Chemicals, School of Chemistry and Chemical Engineering, Bohai University, 19 Keji Road, Jinzhou 121000, China

Abstract

A facile synthesis of novel 1,4-phenylene bridged bis-isoxazolo-, pyrazolo-, and pyrano-fused tropone compounds (2-6) is described, involving the cyclization reaction of 3,3’-{1,4-phenylenebis[(1E)-3-oxoprop-1-ene-1,3-diyl]} bis(tropolone) (1) with hydroxylamine hydrochloride, aromatic hydrazine hydrochlorides, and I2/DMSO/H2SO4 system, respectively. The substrate 1 was obtained via the Claisen-Schmidt condensation reaction between 3-acetyl-tropolone and terephthalaldehyde.