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Communication | Special issue | Vol 86, No. 2, 2012, pp.933-940
Published online, 23rd August, 2012
DOI: 10.3987/COM-12-S(N)77
A NOVEL THREE-COMPONENT COUPLING REACTION OF ARYNES, ISOCYANIDES, AND CYANOFORMATES: A STRAIGHTFORWARD ACCESS TO CYANO-SUBSTITUTED IMINOISOBENZOFURANS

Jing Li, Shintaro Noyori, Masayuki Iwasaki, Kiyohiko Nakajima, and Yasushi Nishihara*

*Department of Chemistry, Graduate School of Natural Science and Technology, Okayama University, 1-1-1 Tsushima-naka, Okayama 700-8530, Japan

Abstract

Iminoisobenzofuran derivatives have been prepared by the palladium-catalyzed three-component coupling reaction of arynes, isocyanides, and cyanoformates in moderate yields.