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Paper | Regular issue | Vol 85, No. 8, 2012, pp.1949-1959
Published online, 29th June, 2012
DOI: 10.3987/COM-12-12511
New Indole Alkaloids from Melodinus henryi

Mariko Kitajima, Satoko Ohara, Noriyuki Kogure, Yuqiu Wu, Rongping Zhang, and Hiromitsu Takayama*

*Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8675, Japan

Abstract

Two new indole alkaloids, melodinoxanine (1) and Nb-methylnortetraphyllicine (2), were isolated from the stems and leaves of Melodinus henryi growing in Yunnan, China. Melodinoxanine (1) is a unique oxindole alkaloid with an extra oxygen atom in the C-ring of a heteroyohimbine skeleton.