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Short Paper | Regular issue | Vol 85, No. 11, 2012, pp.2745-2748
Published online, 3rd September, 2012
DOI: 10.3987/COM-12-12551
Condensation Reaction of Ethyl 4-Oxo-4H-benzo[d][1,3]oxazine-2-carboxylates with Potassium Cyanate: 2,4(1H,3H)-Quinazolinediones Synthesis

Farzad Nikpour,* Forugh Havasi, and Zeinab Arzegar

*Department of Chemistry, Faculty of Science, University of Kurdistan, Sanandaj, Pasdaran Bivd., P.O.Box 66135-416, Iran


The condensation reaction of ethyl 4-oxo-4H-benzo[d][1,3]oxazine-2-carboxylates with acidic solution of potassium cyanate offers a novel and expedient route to the synthesis of 2,4(1H,3H)-quinazolinediones under mild reaction conditions.