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Short Paper | Regular issue | Vol 87, No. 1, 2013, pp.133-145
Published online, 31st October, 2012
DOI: 10.3987/COM-12-12592
Synthesis of Some New 5-Dialkylaminomethylhydantoins and Related Compounds

Fumiko Fujisaki, Mayu Egami, Keiko Toyofuku, and Kunihiro Sumoto*

*Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan

Abstract

In this paper, we describe the synthesis of new 5-dialkylaminomethyl-substituted hydantoin derivatives (3 and 9) from β-aminoalanines (1 or 6) and some chemical properties of the synthesized compounds. A synthetic trial for the preparation of a new twin-drug type molecule (12) is also described.