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Short Paper | Regular issue | Vol 87, No. 3, 2013, pp.637-643
Published online, 7th January, 2013
DOI: 10.3987/COM-12-12631
Isolation and Structure Elucidation of Alkaloids from Pinellia ternata

Zhihao Zhang, Wenjie Li, Ruichao Lin,* Zhong Dai,* and Xiaofeng Li

*Faculty of Chinese Medicine, Macau University of Science and Technolog, Avenida Wai Long, Taipa, Macau 999078, China

Abstract

A new compound, 3-(6,7-dimethoxyisoquinolin-1-yl)-4,7-dimethoxy-3-methylisobenzofuran-1(3H)-one (1) named alkterlactone was isolated from Pinellia ternata, together with four known compounds N-trans-feruloyloctopamine (2), 2'-O-methyladenosine (3), 5'-S-methyl-5'-thioadenosine (4) and 2'-deoxy-thymidine (5). Compounds 2–5 were isolated for the first time from Pinellia ternata. The structures of these compounds were elucidated and characterized on the basis of 1D NMR, 2D NMR and MS data.