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Obituary
Zenichi Yoshida (1925-2023)
Zenichi Yoshida (1925-2023)
Professor. Zenichi Yoshida,
a member of the Honorary Advisors of HETEROCYCLES (1975-1998),
has passed away on May 4, 2023 at the age of 97.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
May 11, 2023
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Short Paper | Regular issue | Vol 87, No. 5, 2013, pp.1127-1132
Published online, 10th April, 2013
Published online, 10th April, 2013
DOI: 10.3987/COM-13-12713
■ New Xanthones from Garcinia bracteata and Their Cytotoxicities
Qiu-Fen Hu,* Deyun Niu, Xiangli Li, Yunhua Qin, Zongyan Yang, Guoli Zhao, Zhongxiu Yang, Xue-Mei Gao,* and Zhangyu Chen
*Key Laboratory of Ethnic Medicine Resource Chemistry, State Ethnic Affairs Commission & Ministry of Education, School of Chemistry and Biotechnology, Yunnan University of Nationalities, Kunming, Jingming South Road, Chenggong New District, Kunming, Yunnan 650500, China
Abstract
Two new xanthones, bracthones A (1) and B (2), together with four known xanthones (3-6) were isolated from the stems of Garcinia bracteata. Their structures were elucidated by spectroscopic methods, including extensive 1D- and 2D- NMR techniques. Compounds 1-6 were tested for their cytotoxicities against five human tumor cell lines (NB4, A549, SHSY5Y, PC3, and MCF7). Compounds 1 and 2 showed high cytotoxicities against PC3 cell with IC50 values of 3.24 and 2.15 μM, respectively.
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