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Short Paper | Regular issue | Vol 87, No. 7, 2013, pp.1537-1543
Published online, 21st May, 2013
DOI: 10.3987/COM-13-12722
Whitmanoside A, a New α-Pyrone Glycoside from the Leech Whitmania pigra

Tao Li, Guo-Cai Wang,* Xiao-Jun Huang, and Wen-Cai Ye*

*College of Pharmacy, Jinan University, 601 West Huangpu Avenue, Guangzhou, 510632, China

Abstract

A new α-pyrone glycoside, whitmanoside A (1), along with eight known compounds, including two furanones (2, 3) and six proline-derived cyclic dipeptides (4-9), were isolated from the dried material of the leech Whitmania pigra. The structures of these compounds were established on the basis of their spectroscopic data and acid hydrolysis. This is the first report on the isolation of these compounds from a leech.