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Review | Regular issue | Vol 87, No. 7, 2013, pp.1415-1439
Published online, 27th May, 2013
DOI: 10.3987/REV-13-768
Recent Application of 4-Hydroxycoumarin in Multi-Component Reactions

Ghodsi Mohammadi Ziarani* and Parvin Hajiabbasi

*Department of Chemistry, Alzahra University, Vanak Square, Tehran, P.O. Box number 19938939973, Iran

Abstract

4-Hydroxycoumarin has been utilized in many heterocyclic preparations such as indole-containing compounds, furo- and pyran-annulated, and spiro-compounds. In addition, significant places of its derivatives as pharmaceutical compounds cause it more important. There are a diversity of multi-component reactions of this useful reagent which we highlight the recent reports of them in this review. Also, herein some asymmetric syntheses via 4-hydroxycoumarin is discussed.