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■ Facile Access to Novel 3-Acylimidazo[1,2-a]pyrimidines under Microwave Irradiation

Mohamed R. Shaaban*

*Department of Chemistry, Faculty of Science, Cairo University, Giza 12013, Egypt

Abstract

Treatment of mono-, bis- and tris(ω-bromoacetophenone) derivatives with N,N-dimethylformamidine derivative of 2-aminopyrimidine, afforded the novel 3-aroyl or heteroyl derivatives of imidazo[1,2-a]pyrimidine, bis(imidazo[1,2-a]pyrimidine) and tris(imidazo[1,2-a]pyrimidine) derivatives, respectively, under both conventional and microwave conditions.