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Short Paper | Regular issue | Vol 87, No. 10, 2013, pp.2047-2052
Published online, 30th August, 2013
DOI: 10.3987/COM-13-12773
Alkaloids from Melodinus suaveolens

Ting-Ting Zhang, Zhi-Wen Liu, Wen-Jing Wang, Yong-Bin Tong, Fang-Fang Xu,* Jing-Quan Yuan, Bo Liu, Xiao-Qi Zhang,* and Wen-Cai Ye

*Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, 601 West Huangpu Avenue, Guangzhou, 510632, China

Abstract

Two new quinoline alkaloids, 14,15-β-epoxyscandine (3) and meloscine N-oxide (6), along with six known alkaloids scandine (1), scandine N-oxide (2), meloscandonine (4), meloscine (5), tubotaiwine (7), polyneuridine (8) were isolated from the twigs and leaves of Melodinus suaveolens. The structures of the new compounds were elucidated on the basis of spectroscopic methods and circular dichroism experiments.