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Paper | Regular issue | Vol 87, No. 11, 2013, pp.2249-2266
Published online, 3rd October, 2013
DOI: 10.3987/COM-13-12799
A Novel Synthetic Approach towards 1H-Pyrazole-5-carboxylic Acid Derivatives Using 4-(4-Methylbenzoyl)-5-(4-methylphenyl)furan-2,3-dione

Elif Korkusuz,* Ismail Yıldırım, and Ertan Şahin

*Kayseri Vocational College, Erciyes University, Kayseri 38039, Turkey

Abstract

The 1H-pyrazole-5-carboxylic acid derivatives were obtained by reactions of 4-(4-methylbenzoyl)-5-(4-methylphenyl)furan-2,3-dione with 2,4-dinitrophenyhydrazine. So, new derivatives of 1H-pyrazole-5-carboxylic acid which are potential biological active compounds, were synthesized for the first time. The structures of all new synthesized products were characterized by IR, 1H-, 13C NMR, APT, and 2D NMR (HETCOR, COSY) spectroscopic data and elemental.