HETEROCYCLES

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

■ Chromone Derivatives from the Leaves of Nicotiana tabacum and Their Anti-Tobacco Mosaic Virus Activities

Guangyu Yang, Wei Zhao, Tao Zhang, Yuanxing Duan, Zhihua Liu, Mingming Miao, and Yongkuan Chen*

*Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, China

Abstract

Two new chromone derivatives, 5-hydroxy-9-methyl-1-(2-oxopropyl)benzo[β]oxepin-7(2H)-one (1), 5-hydroxy-2-methoxy-9-methyl-1-(2-oxopropyl)benzo[β]oxepin-7(2H)-one (2), together with five known chromone derivatives (3-7), were isolated from the leaves of Nicotiana tabacum. Their structures were elucidated by spectroscopic methods, including extensive 1D- and 2D-NMR techniques. Compounds 1-7 were tested for their anti-tobacco mosaic virus (anti-TMV) activities. The results showed that compound 2 showed high anti-TMV activity with inhibition rate of 31.5%. It inhibition rate is high than that of positive control. The other compounds also showed potential anti-TMV activities with inhibition rates in the range of 11.2 – 23.5%, respectively.