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Review | Regular issue | Vol 89, No. 5, 2014, pp.1125-1157
Published online, 10th January, 2014
DOI: 10.3987/REV-13-790
Heterocyclization with Some Heterocyclic Diamines: Synthetic Approaches for Nitrogen Bridgehead Heterocyclic Systems

Magdy A. Ibrahim* and Nasser M. El-Gohary

*Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, Cairo 11711, Egypt

Abstract

This review represents the methods developed for the synthesis of a variety of nitrogen bridgehead heterocyclic systems such as [1,2,4]triazolo[1,5-a]pyridines, pyrido[1,2-b][1,2,4]triazines, pyrido[1,2-b][1,2,4]triazepines, pyrazolo [1,5-b][1,2,4]triazole, pyrazolo[1,5-b][1,2,4]triazine, pyrazolo[1,5-b][1,2,4]triazepine, [1,2,4]triazolo[3,4-b][1,2,4]triazine, [1,2,4]triazolo[4,3-b][1,2,4]triazepines, pyrimido[3,4-b][1,2,4]triazine from the heterocyclization of some heterocyclic diamines with a variety of electrophilic reagents.