Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Short Paper | Regular issue | Vol 89, No. 5, 2014, pp.1211-1220
Published online, 24th March, 2014
DOI: 10.3987/COM-14-12960
■ A Facile One-Pot Synthesis of Model Diethyl 6,6'-Dioxotetrahydro-5,5'-bi(1,2,4-triazine)-5,5'-dicarboxylates

Mustafa M. El-Abadelah,* Hanan H. Mohammed, Mohammed M. Abadleh, Salim S. Sabri, and Firas F. Awwadi

*Department of Chemistry, Faculty of Science, The University of Jordan, Amman 11942, Jordan

Abstract

The reaction of diethyl aminomalonate with nitrile imine 1,3-dipolar species 1a,b follows a stereospecific path to deliver the racemic tetrahydro-6,6'-dioxo-5,5'-bi(1,2,4-triazine)-5,5'-dicarboxylates 4a,b, whilst the corresponding diastereomeric meso forms (5R, 5'S) could not be detected in the reaction product. Structural assignments for these novel heterocyclic dimers are based on microanalytical and spectral (MS, NMR) data, and further confirmed by X-ray diffraction analysis of single crystal for 4a.