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Short Paper | Regular issue | Vol 89, No. 5, 2014, pp.1237-1244
Published online, 27th March, 2014
DOI: 10.3987/COM-14-12969
■ New Gallic Acid Glycosides from Mallotus plicatus

Kongsin Luangruangrong, Boonchoo Sritularak, Vimolmas Lipipun, and Kittisak Likhitwitayawuid*

*Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Phayathai Road, Pathumwan, Bangkok 10330, Thailand

Abstract

From the stem bark of Mallotus plicatus (Müll.Arg.) Airy Shaw, two new gallic acid glycosides, namely bergenin-8-O-α-L-rhamnoside (1) and seco-bergenin-8-O-α-L-rhamnoside (2) were isolated along with seven known compounds (3-9). The structures of the new isolates (1 and 2) were elucidated through analysis of their 1D- and 2D-NMR, and MS spectral properties, as well as chemical evidence. seco-Bergenin-8-O-α-L-rhamnoside (2) and protocatechuic acid (7) showed weak inhibitory activity against Herpes simplex virus, whereas the other compounds were devoid of such activity.