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Short Paper | Regular issue | Vol 89, No. 11, 2014, pp.2619-2626
Published online, 30th October, 2014
DOI: 10.3987/COM-14-13103
Two New Triterpene Saponins from the Tubers of Stachys sieboldii

Hyeon Kyung Cho, Chung Sub Kim, Won Se Suh, Ki Hyun Kim, and Kang Ro Lee*

*Natural Products Laboratory, School of Pharmacy, Sungkyunkwan University, 300 Chunchun-dong, Jangan-ku, Suwon 440-746, Korea

Abstract

Chemical investigation of the MeOH extract of tubers of Stachys sieboldii MIQ. (Labiatae) led to two new triterpene saponins (1 and 2) named sieboldii saponin B and C, together with six known triterpenes (3-8). The structural elucidation of the new compounds was based on MS, 1H- and 13C-NMR, and 2D NMR analysis (1H-1H COSY, HMQC, HMBC, and NOESY) as well as acid hydrolysis. All the isolated compounds 1-8 were reported from this source for the first time.