Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,320 (Yen only)
Period: This Article can be accessed for 7 days.

Short Paper | Regular issue | Vol 91, No. 9, 2015, pp.1781-1796
Published online, 6th August, 2015
DOI: 10.3987/COM-15-13267
Regioselective Synthesis of Pyrazoles and Pyrazolo[1,5-a]Pyrimidines: Structural Characterization by HMBC NMR

Abdullah S. Al-Bogami and Tamer S. Saleh*

*Department of Green Chemistry, National Research Centre, El-Tahrir Street, Dokki, Giza 12622, Egypt

Abstract

In this study a series of novel pyrazoles and pyrazolo[1,5-a]pyrimidines with a sulfone moiety incorporated the coumarin ring were efficiently synthesized. These pyrazoles and pyrazolo[1,5-a]pyrimidines were synthesized by treating enaminone derivative of β-ketosulfone (3-(2-tosylacetyl)-2H-coumarin) with substituted hydrazines and 5-aminopyrazole derivatives, respectively under microwave irradiation. The structures of the products thus obtained were characterized by 2D NMR (HMBC).