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Short Paper | Regular issue | Vol 92, No. 6, 2016, pp.1132-1136
Published online, 27th April, 2016
DOI: 10.3987/COM-16-13465
A One-Pot Synthesis of Phaitanthrin E Through Intermolecular Condensation/Intramolecular Aryl C-H Amination Cascade

Tomoki Itoh, Takumi Abe, Tominari Choshi, Takashi Nishiyama, and Minoru Ishikura*

*School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido 061-0293, Japan

Abstract

A one-pot synthesis of phaitanthrin E starting from methyl indole-3-carboxylate and isatoic anhydride through intermolecular condensation/intramolecular aryl C-H amination cascade was developed.