Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Review | Special issue | Vol 95, No. 1, 2017, pp.116-126
Published online, 5th December, 2016
DOI: 10.3987/REV-16-SR(S)3
Total Synthesis of (+)-Linoxepin

Minami Odagi,* Kota Furukori, Yoshiharu Yamamoto, and Kazuo Nagasawa*

*Department of Biotechnology and Life Science, Faculty of Technology, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan

Abstract

(+)–Linoxepin is a lignan-type natural product with a synthetically challenging fused dihydronaphthalene/dihydroxepine structure. It also has multiple biological activities, including antitumor, antioxidant, and antiviral activities. Here, we review three recent total syntheses of (+)–linoxepin.