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Short Paper | Special issue | Vol 95, No. 2, 2017, pp.1177-1183
Published online, 24th January, 2017
DOI: 10.3987/COM-16-S(S)66
Synthesis of 2-Aroyl-1-methyl-1H-imidazoles Using Aryl Carboxylic Acids

Kin-ichi Oyama,* Noriyuki Watanabe, and Kumi Yoshida*

*Graduate School of Information Science, Nagoya University, Chikusa, Nagoya, 464-8601, Japan


A new and useful reaction for the synthesis of 2-aroyl-1-methyl-1H-imidazoles using free aryl carboxylic acids was developed. This method was applicable to naphthoic acid and benzoic acid derivatives to give each target compound with up to 80% yield.