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Communication | Regular issue | Vol 94, No. 2, 2017, pp.237-240
Published online, 26th January, 2017
DOI: 10.3987/COM-16-13637
One-Pot Synthesis of Benz[f]Indolo[3,2-c]isochromeno- 5,7,13-trione Derivatives from 2-Amino-1,4-naphtho-quinones and Ninhydrin

Ting Zhou, Guang-Yu Pan, Dao-Lin Wang,* and Jian-Hua Qian

*Liaoning Key Laboratory of Synthesis and Application of Functional Compound, College of Chemistry & Chemical Engineering, Bohai University, Jinzhou 121001, China


An efficient method for the preparation of novel benz[f]indolo[3,2-c]-isochromeno-5,7,13-triones 3 was described. The construction of this new pentacyclic system was achieved undergo a domino reaction of 2-amino-1,4-naphthoquinones 1 with ninhydrin 2 in one-pot with good yields.