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Short Paper | Regular issue | Vol 98, No. 1, 2019, pp.79-87
Published online, 31st January, 2019
DOI: 10.3987/COM-18-S(F)81
Ring-Opening Metathesis of N-Alkenyl β-Lactams

Sambasivarao Kotha,* Sunil Pulletikurti, and Yuvaraj Dommaraju

*Department of Chemistry, Indian Institute of Technology-Bombay, Powai, Mumbai-400 076, India

Abstract

We have synthesized a new class of N-alkenylated β-lactam derivatives and studied their metathetic behavior. Here, ring-opening metathesis is more favorable than ring-rearrangement metathesis. Molecular modelling studies revealed that the orientation of two olefinic moieties of β-lactam derivatives are far apart and therefore ring-rearrangement metathesis did not occur and ring-opening metathesis is only feasible.