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Review | Special issue | Vol 99, No. 1, 2019, pp.54-72
Published online, 17th October, 2018
DOI: 10.3987/REV-18-SR(F)2
Chemistry of Nitroaziridines

Feiyue Hao and Nagatoshi Nishiwaki*

*School of Environmental Science and Engineering, Kochi University of Technology, Tosayamada-cho, Kami, Kochi, 782-8502, Japan

Abstract

This review article introduced synthetic procedures for the preparation of structurally diverse nitroaziridines. In addition, this article also summarized reactivity of nitroaziridines caused by the inherent strain and high electrophilicity of the small ring. These properties facilitate their use as a functionalized building blocks in synthetic and medicinal chemistry.