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Review | Regular issue | Vol 98, No. 1, 2019, pp.3-18
Published online, 18th December, 2018
DOI: 10.3987/REV-18-895
Recent Advancements in the Synthesis of Half-Esters and Their Applications

Jianjun Shi and Satomi Niwayama*

*Division of Sustainable and Environmental Engineering, Graduate School of Engineering, Muroran Institute of Technology, 27-1, Mizumoto-cho, Muroran, Hokkaido, 050-8585, Japan

Abstract

Half-esters are important building blocks for the synthesis of pharmaceuticals, polymers and natural products. Therefore, synthetic methodologies for both chiral and racemic half-esters have been actively investigated for decades. This short review summarizes recent progress in the synthesis of half-esters and their applications including the studies from our laboratories.