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Review | Regular issue | Vol 98, No. 1, 2019, pp.19-62
Published online, 29th January, 2019
DOI: 10.3987/REV-18-898
Divergent Synthesis of Steroid Analogs from Steroidal β-Formylenamides, Conjugated Enones and β-Formylvinyl Halides

Geetmani S. Nongthombam and Romesh C. Boruah*

*Chemical Science and Technology Division, CSIR-North East Institute of Science & Technology, Jorhat, Assam, India 785006

Abstract

In the past two decades, our laboratory has been actively engaged in the design and synthesis of novel heterosteroidal analogues. Three functional groups namely β-formylenamide, conjugated enone and β-formylvinyl halide were primarily employed in various reactions to afford a library of novel heterosteroids. The synthetic strategies have been concomitantly utilized in the relevant non-steroidal β-formylenamides, conjugated enones and β-formylvinyl halides.