HETEROCYCLES

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

■ Synthesis of Optically Acitve γ-Lactams by Palladium Catalyzed Asymmetric Dicarbonylation Reaction of N-Arylsufonyl Homoallylic Amines

Ryosuke Takahashi, Nga Hang Thi Phan, Takuya Suga, Takahiro Soeta, and Yutaka Ukaji*

*Division of Material Sciences, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma, Kanazawa, Ishikawa 920-1192, Japan

Abstract

Optically active γ-lactams were prepared by asymmetric dicarbonylation reaction of N-arylsulfonyl homoallylic amines catalyzed by palladium in the presence of copper(I) triflate. By the use of benzyl-substituted bioxazoline ligand, the corresponding γ-lactams were obtained with enantioselectivities of up to 67% ee.