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Review | Regular issue | Vol 98, No. 12, 2019, pp.1678-1706
Published online, 26th December, 2019
DOI: 10.3987/REV-19-920
Microwave-Assisted Synthesis of 1,3,5-Triazines: Efficient Approaches to Therapeutically Valuable Scaffold

Ahmad Junaid and Anton V. Dolzhenko*

*School of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, Selangor Darul Ehsan 47500, Malaysia

Abstract

1,3,5-Triazine ring is an important scaffold for the construction of new biologically active compounds. Microwave irradiation has found an extensive application in organic and medicinal chemistry accelerating reactions and drug discovery process. This review systematizes methods for the microwave-assisted construction of 1,3,5-triazine ring and discusses their advantages and disadvantages over methods based on the conventional heating.