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Short Paper | Regular issue | Vol 102, No. 8, 2021, pp.1579-1587
Published online, 17th June, 2021
DOI: 10.3987/COM-21-14482
Diterpenoid Alkaloids from Aconitum leucostomum and Their Antifeedant Activity

Jue Wang, Jin-bu Xu, Hong-bo Yang, Feng Gao, Xian-li Zhou, Lin Chen,* and Shuai Huang*

*School of Life Science and Engineering, Southwest Jiaotong University, Southwest Jiaotong University, Chengdu, 610031, China


Two new diterpenoid alkaloids and eight known ones were isolated from the root of Aconitum leucostomum. Their structures were elucidated on the basis of extensive spectroscopic analyses such as HR-ESI-MS, 1D NMR and 2D NMR spectra. Compounds 1, 2, 5, 6 and 8 were tested for their antifeedant activity against Spodoptera exigua Hübner, and compound 2 showed antifeedant activity with an effective concentration for 50% feeding reduction (EC50) at 1.54 mg/cm2.