HETEROCYCLES

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

■ A Comprehensive Study of Pyrimidine and Its Medicinal Applications

Vikas Vilas Borge* and Juilee Vaze

*Department of Chemistry, University of Mumbai, Vidyanagari, Kalina, Mumbai-400098, India

Abstract

Pyrimidine is a heterocyclic aromatic organic compound which is versatile lead compound for designing potent therapeutic agents. Different pyrimidine derivatives have been synthesized by various conventional methods and also from green methods. The pyrimidine moiety widely occurs in biologically occurring compounds, such as nucleic acids components, folic acid and vitamin B1 etc. This compound has various biological activities like anticancer, antitubercular, antimicrobial, antifungal, antibacterial, antioxidant, anticonvulsant, analgesic, CNS depressant, anti-inflammatory, anti-HIV, antihelmentic and herbicidal activity. Available data represents pyrimidine being heterocyclic six membered ring systems has various pharmacological actions and synthesis of pyrimidine and their derivatives are discussed.