Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 104, No. 3, 2022, pp.495-511
Published online, 22nd December, 2021
DOI: 10.3987/COM-21-14592
A New C,C-Linked Functionalized Bipyrazole: Synthesis, Crystal Structure, Spectroscopies and DFT Studies. Evaluation of the Antibacterial Activity and Catalytic Properties

Ibrahim Bouabdallah, Tarik Harit,* Yahya Rokni, Mahmoud Rahal, Monique Tillard, Driss Eddike, Abdeslam Asehraou, and Fouad Malek*

*Laboratory of Applied Chemistry and Environment, Faculty of Sciences, Mohammed First University Bd Mohamed VI, 60 000 Oujda, Morocco


The synthesis of new C,C-linked functionalized bipyrazole is reported. Its molecular structure has been confirmed by spectroscopic and spectrometric methods and its single crystal structure determined by X-ray analysis. The ligand 2 has been subjected to DFT and TD-DFT theoretical calculations and results are consistent with the experimental chemical analyses. The compound possesses no antibacterial activity up to 256 g/mL. However, its complexes with copper(II) salts are found to be good catalysts for the oxidation of 3,5-di-tert-butylcatechol (DTBC) into 3,5-di-tert-butylquinone (DTBQ) with a rate varying from 9.58 μmol L-1min-1 for the 2-[Cu(MeCO2)2] complex to 5.27 μmol L-1min-1 for the 2-[Cu(BF4)2] complex.