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Review | Regular issue | Vol 106, No. 4, 2023, pp.561-593
Published online, 26th January, 2023
DOI: 10.3987/REV-22-998
3-[2-Oxo-2H-chromen-3(6)(8)-yl]-1-aryl/heteroaryl-1H-pyrazole-4-carbaldehydes: Synthesis, Reactions and Applications

Ayat K. Alsolimani, Mohammed A. Assiri, and Tarik E. Ali*

*Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, Cairo, Egypt


The chemistry of 3-(2-oxo-2H-chromen-3(6)(8)-yl)-1-aryl/heteroaryl-1H-pyrazole-4-carbaldehydes has gained increased interest in both synthetic organic and biological fields, since a large number of developments in the use of such compounds seem to be of considerable value. This review describes all the available synthetic methods for diverse 3-(2-oxo-2H-chromen-3(6)(8)-yl)-1-aryl/ heteroaryl-1H-pyrazole-4-carbaldehydes in the literature survey. It also summarizes thier chemical behaviors as building blocks towards a variety of chemical reagents to construct related compounds as well as their biological applications.